Civil Service Exam Mains – IAS Exam Mains 2017 Syllabus for Zoology Paper II – Paper I
1. Cell Biology :
- Structure and function of cell and its organelles ( nucleus, plasma membrane, mitochondria, Golgi bodies, endoplasmic reticulum, ribosomes, and lysosomes ), cell division ( mitosis and meiosis ), mitotic spindle and mitotic apparatus, chromosome movements, chromosome type polytene and lambrush, organization of chromatin, heterochromatin, Cell cycle regulation.
- Nucleic acid topology, DNA motif, DNA replication, transcription, RNA processing, translation, protein foldings and transport.
2. Genetics :
- Modern concept of gene, split gene, genetic regulation, genetic code.
- Sex chromosomes and their evolution, sex determination in Drosophila and man.
- Mendel’s laws of inheritance, recombination, linkage, multiple alleles, genetics of blood groups, pedigree analysis, hereditary diseases in man.
- Mutations and mutagenesis.
- Recombinant DNA technology; plasmid, cosmid, artificial chromosomes as vectors, transgenic, DNA cloning and whole animal cloning ( principles and methods ).
- Gene regulation and expression in prokaryotes and eukaryotes.
- Signal molecules, cell death, defects in signaling pathway and consequences.
- RFLP, RAPD and AFLP and application of RFLP in DNA finger printing, ribozyme technologies, human genome project, genomics and protomics.
3. Evolution :
- Theories of origin of life.
- Theories of evolution; Natural selection, role of mutations in evolution, evolutionary patterns, molecular drive, mimicry, variation, isolation and speciation.
- Evolution of horse, elephant and man using fossil data.
- Hardy-Weinberg Law.
- Continental drift and distribution of animals.
4. Systematics :
- Zoological nomenclature, international code, cladistics, molecular taxonomy and biodiversity.
5. Biochemistry :
- Structure and role of carbohydrates, fats, fatty acids and cholesterol, proteins and amino-acids, nucleic acids. Bioenergetics.
- Phosphorylation, energy conservation and release, ATP cycle, cyclic AMP – its structure and role.
- Hormone classification ( steroid and peptide hormones ), biosynthesis and functions.
- Enzymes : types and mechanisms of action.
- Vitamins and co-enzymes
- Immunoglobulin and immunity.
6. Physiology ( with special reference to mammals ) :
- Composition and constituents of blood; blood groups and Rh factor in man, factors and mechanism of coagulation, iron metabolism, acid-base balance, thermo-regulation, anticoagulants.
- Haemoglobin : Composition, types and role in transport of oxygen and carbon dioxide.
- Digestion and absorption: Role of salivary glands, liver, pancreas and intestinal glands.
- Excretion : nephron and regulation of urine formation; osmo-regulation and excretory product.
- Muscles : Types, mechanism of contraction of skeletal muscles, effects of exercise on muscles.
- Neuron : nerve impulse – its conduction and synaptic transmission, neurotransmitters.
- Vision, hearing and olfaction in man.
- Physiology of reproduction, puberty and menopause in human.
7. Developmental Biology :
- Gametogenesis; spermatogenesis, composition of semen, in vitro and in vivo capacitation of mammalian sperm, Oogenesis, totipotency; fertilization, morphogenesis and morphogen, blastogenesis, establishment of body axes formation, fate map, gestulation in frog and chick; genes in development in chick, homeotic genes, development of eye and heart, placenta in mammals.
- Cell lineage, cell-to cell interaction, Genetic and induced teratogenesis, role of thyroxine in control of metamorphosis in amphibia, paedogenesis and neoteny, cell death, aging.
- Developmental genes in man, in vitro fertilization and embryo transfer, cloning.
- Stem cells : Sources, types and their use in human welfare.
- Biogenetic law.