Indian Civil Service Exams (CSE) Syllabus - UPSC Exams

UPSC Exams Indian Civil Services Syllabus for Main Exams: Medical Science

Paper-I

Section-A

I.Human Anatomy : Gross and microscopic anatomy and movements of shoulder, hip and knee joints; Blood supply, nerve innervations of hand, Lymphatic system; Karyotyping, medical genetics; Electron microscopic structure of glomerulous and muscle; Gross and microscopic anatomy and blood supply of lungs, heart, kidneys, liver, testis and uterus; Gross anatomy of pelvis, perineum and inguinal region. Cross-sectional anatomy of the body and mid-thoracic, upper abdominal, mid-abdominal and pelvic regions.

Embryology : Major steps in the development of lung, heart, kidney, urinary bladder, uterus, ovary, testis and their common congenital abnoirmalities; Placenta and placental barrier.

Anatomy of central and peripheral autonomic nervous system :

Neural pathways for cutaneous sensations and vision; Cranial nerves, distribution and clinical significance; Anatomy of autonomic control of gastrointestinal, respiratory and reproductive systems.
II. Human Physiology : Central, peripheral and autonomic nervous. system; Nerve and muscle excitation, conduction and transmission of impulse, mechanism of contraction, neurovascular transmission, EMG; Synaptic transmission, reflexes, control of equilibrium, posture and muscle tone descendig pathways, functions of creebellum, basal ganglia, reticular formation, hypothalamus limbic system and cerebral cortex; Physiology of sleep and consciousness, EEG.; Higher functions of the brain; Vision and hearing.

Endocrine system : Mechanism of action of hormones, formation, secretion, transport, metabolism, functions and regulations of secretion of pancreas and pituitary glands.
Physiology of reproductive system : menstrual cycle, lactation, pregnancy.
Blood : Development, regulations and fate of blood cells.

Cardio-vascular, respiratory gastro-intestinal and renal physiology : Cardiac excitation, spread of cardiac impulse, ECG., cardiac output, blood pressure, regulation of cardiovascular functions; Mechanics of respiration and regulation of respiration; Digestion and absorption of food, regulation of secretion and motility of gastrointesinal tract; Glomerular and tubular fucntions of kidney.
III. Biochemistry : pH and pK Hendrson-Hassebalch Equation; Properties and regulation of enzyme activity, role of high energy phosphates in bioenergetics; Sources, daily requirements, action and toxicity of vitamins; Metabolism of lipids, carbohydrates, proteins, disorders of their metaboilism; Chemical nature, structure, synthesis and fucntions of nucleic acids and proteins; Distribution and regulation of body water and minerals including trace elements; Blood Gas Analysis, GTT, Immuno electrophorises, molecular structure of muscle contractile protein, oestrogen receptors.

Section-B

I. Pathology : Rection of cell and tissue of injury, inflammation and repair , disturbances of growth and cancer. genetic diseases; Pathogenesis and histopathology of Rheumatic and ischaemic heart disease; Bronchogenic carcinoma, carcinoma breast, oral cancer, cancer colon. Lymphoma, leukaemia, liver cancer, meningioma and meningitis; Etiology, pathognesis and histopathology of - Peptic ulcer, cirrhosis liver glomerulonephritis, lobar pneumonia, acute osteomyelitis, hepatitis, acute pancreatitis.
II. Microbiology : Growrth of micro-organisms, sterilization and disinfection, bacterial genetics, virus-cell interactions; Immunological principles, acquired immunity, immunity in infections cause by viruses; Diseases caused by and laboratory diagnosis of Staphylococcus, enterococcus, salmonella, shigella, secheichiza, pseudomonos, vibrio, adenoviruses, herpes viruses (including rubella_, fungi, protozoa, helminths, leptospiral infection.
III. Pharmacology : Drug receptor instruction, mechanism of drug action; Mechanism of action, dosage, metabolism and side effects of - Pilocarpine, terbutaline, metoprolol diazepam, acetylsalicylic acid, ibuprofen, furosemide, metronidazole. Chloroquin. Mechanism of action, dosage and toxicity of- Ampicillin, Cephalosporins, 1,2,3,4,th generations, Aminoglycoside, Doxycycline, chloramphenicol, rifampin, Calcium channel blocker, beta blocker, ace inhibitors, immunosuppressive therapy. Indications, dosage, side-effects and contraindictions of- Methortrexate, vincristin, tamoxifen. Classification, route of administration, mechanism of action and side effects of - General anaesthetics, hypnotics, analgesics, Anti-viral, anti-fungal drugs.
IV. Forensic Medicine and Toxicology : Forensic examination of injuris and wounds; Physical and chemical examination of blood and seminal stains; Organo phosphorous poisoning, sedative overdose, hanging, drowning, burns, snake envenomation.